RNase L Antibody (2E9)

Product Specs
ItemRNase L Antibody (2E9) - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberNB100-351
ImmunogenPurified full-length recombinant human RNaseL produced in insect cells. [UniProt# Q05823]
Concentration1.0 mg/ml
ClonalityMonoclonal
ReactivityHuman, Hamster, Primate
IsotypeIgG1 Kappa
FormatPBS
ApplicationsWestern Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
TargetRNase L
Quantity0.1 ml (also 0.025 ml)
Conjugate/TagUnconjugated
HostMouse
Clone2E9
Brand/TrademarkNovus Biologicals, a Bio-Techne Brand
PurityProtein G purified
Molecular Weight83 kDa
Research AreaChromatin Research, Cytokine Research, DNA replication Transcription Translation and Splicing, Immunology, Innate Immunity, Prostate Cancer, Protein Kinase
NCBI Full Gene Nameribonuclease L
NCBI Gene AliasesRNS4, PRCA1
Antibody TypePrimary Antibodies
ValidationKnockout Validated
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: http://www.novusbio.com

(1) RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleusPLoS pathogensNovember 1, 2022Burke JM, Ripin N, Ferretti MB, St Clair LA, Worden-Sapper ER, Salgado F, Sawyer SL, Perera R, Lynch KW, Parker R.was performed as described in [13]. Mouse anti-RNase L antibody 2E9 (Novus Biologicals catalog no. NB100-351) was used at 1:1500. Histone H3 antibody (Thermo Fisher Scientific; NB500-171) was used at 1:1000. Mouse

(2) RNA is required for the integrity of multiple nuclear and cytoplasmic membrane-less RNP granulesThe EMBO journalMay 2, 2022Decker CJ, Burke JM, Mulvaney PK, Parker R.

(3) A ribosomal RNA fragment with 2',3'-cyclic phosphate and GTP-binding activity acts as RIG-I ligandNucleic acids researchOctober 9, 2020Jung S, von Thülen T, Yang I, Laukemper V, Rupf B, Janga H, Panagiotidis GD, Schoen A, Nicolai M, Schulte LN, et al.

(4) RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granulesThe Journal of biological chemistryFebruary 7, 2020Burke JM, Lester ET, Tauber D, Parker R.no. 13233) was used at 1:500 for IFA. Mouse anti-RNase L antibody 2E9 (Novus Biologicals catalog no. NB100-351) was used at 1:1500 for immunoblot analyses. Mouse monoclonal anti-G3BP antibody (Abcam catalog no.

(5) RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAsMolecular cellSeptember 19, 2019Burke JM, Moon SL, Matheny T, Parker R.sanger sequencing (Quintarabio or Genewiz). Antibodies Mouse anti-RNase L Antibody 2E9 (Novus Biologicals: NB100-351) was use at 1:1500 for immunoblot analyses. Rabbit anti-IRF3 (Abcam: ab25950) was used at 1:1000 for

(6) Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elementsNucleic acids researchSeptember 1, 2012Al-Haj L, Blackshear PJ, Khabar KS.

(7) RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulationCell death and differentiationSeptember 1, 2012Fabre O, Salehzada T, Lambert K, Boo Seok Y, Zhou A, Mercier J, Bisbal C.

(8) Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infectionJournal of immunology (Baltimore, Md. : 1950)December 15, 2009Lin RJ, Yu HP, Chang BL, Tang WC, Liao CL, Lin YL.

(9) Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-RegulationNucleic acids researchJune 1, 2009Al-Ahmadi W, Al-Ghamdi M, Al-Haj L, Al-Saif M, Khabar KS.

(10) A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase LJournal of virologyJune 1, 2007Han JQ, Townsend HL, Jha BK, Paranjape JM, Silverman RH, Barton DJ.

(11) Germline mutations in the ribonuclease L gene in families showing linkage with HPC1Nature geneticsFebruary 1, 2002Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, et al.

(12) A bipartite model of 2-5A-dependent RNase LThe Journal of biological chemistryAugust 29, 1997Dong B, Silverman RH.

(13) Elevated levels of 2',5'-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesisClinical cancer research : an official journal of the American Association for Cancer ResearchNovember 1, 1995Wang L, Zhou A, Vasavada S, Dong B, Nie H, Church JM, Williams BR, Banerjee S, Silverman RH.

(14) 2-5A-dependent RNase molecules dimerize during activation by 2-5AThe Journal of biological chemistryFebruary 24, 1995Dong B, Silverman RH.

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RNase L Antibody (2E9) - BSA Free

RNase L Antibody (2E9) - BSA Free

RNase L Antibody (2E9) - BSA Free from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (14)

Reviews

RNase L Antibody (2E9) - BSA Free from Novus Biologicals, a Bio-Techne Brand

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